Including Data in teal Applications

General data

A teal_data object is created by calling the teal_data function and passing data objects as name:value pairs.

library(teal)

# create teal_data
data <- teal_data(iris = iris, cars = mtcars)

Note that iris and cars have been added to the datanames property of data (see datanames property).

This is sufficient to run a teal app.

# build app
app <- init(
  data = data,
  modules = example_module()
)

# run app
shinyApp(app$ui, app$server)

Reproducible data

A teal_data object stores data in a separate environment. Therefore, modifying the stored datasets requires that processing code be evaluated in that environment. Following that logic, one can create an empty teal_data object and populate it by evaluating code. This can be done using the eval_code function or, more conveniently, using the within function.

# create empty object
data_empty <- teal_data()

# run code in the object
data_populated_1 <- eval_code(data_empty, code = "iris <- iris
                                                  cars <- mtcars")
# alternative
data_populated_2 <- within(data_empty, {
  iris <- iris
  cars <- mtcars
})

The key difference between eval_code and within is that the former accepts code as character vector or language objects (calls and expressions), while within accepts only inline code. See ?qenv for more details.

Note that in the first example data was created by passing data objects, so the code that was used to create the data objects is unknown and therefore the process cannot be reproduced. Inspecting code the in the app created above reveals a note that the preprocessing code is absent.

The necessary code can be supplied to the code argument of the teal_data function.

data_with_code <- teal_data(
  iris = iris, cars = mtcars,
  code = "iris <- iris
          cars <- mtcars"
)

Keep in mind this code is not executed in the teal_data’s environment, so it may not reproduce the environment. Such an object is considered unverified (see verified property).

If reproducibility is required, we recommend creating an empty teal_data object and then evaluating code.

# not run
data_from_file <- teal_data()
data_from_file <- eval_code(data, readLines("<path_to_file>"))

Creating data in-app

The one departure from passing a teal_data object to init is when the data does not exist in the environment where the app is run, e.g. when it has to be pulled from a remote source. In those cases a teal_data_module must be used. See this vignette for a detailed description.

ADaM data

The ADaM data model, defined in CDISC standards, specifies relationships between the subject-level parent dataset and observation-level child datasets. The cdisc_data function takes advantage of that fact to automatically set default joining keys (see join_keys property). In the example below, two standard ADaM datasets (ADSL and ADTTE) are passed to cdisc_data.

# create cdisc_data
data_cdisc <- cdisc_data(ADSL = teal.data::rADSL, ADTTE = teal.data::rADSL)

names(data_cdisc)
#> [1] "ADSL"  "ADTTE"
join_keys(data_cdisc)
#> A join_keys object containing foreign keys between 2 datasets:
#> ADSL: [STUDYID, USUBJID]
#>   <-- ADTTE: [STUDYID, USUBJID]
#> ADTTE: [STUDYID, USUBJID, PARAMCD]
#>   --> ADSL: [STUDYID, USUBJID]

app <- init(
  data = data_cdisc,
  modules = example_module()
)
shinyApp(app$ui, app$server)

MultiAssayExperiment data

The MultiAssayExperiment package offers a data structure for representing and analyzing multi-omics experiments that involve multi-modal, high-dimensionality data, such as DNA mutations, protein or RNA abundance, chromatin occupancy, etc., in the same biological specimens.

The MultiAssayExperiment class is described in detail here.

MultiAssayExperiment objects (MAEs) are placed in teal_data just like normal objects.

library(MultiAssayExperiment)
utils::data(miniACC)

data_mae <- teal_data(MAE = miniACC)

app <- init(
  data = data_mae,
  modules = example_module()
)
shinyApp(app$ui, app$server)

Due to the unique structure of a MAE, teal requires special considerations when building teal modules. Therefore, we cannot guarantee that all modules will work properly with MAEs. The package teal.modules.hermes has been developed specifically with MAE in mind and will be more reliable.

The filter panel supports MAEs out of the box.

join_keys

Using relational data requires specifying joining keys for each pair of datasets. Primary keys are unique row identifiers in individual datasets and thus should be specified for each dataset. Foreign keys describe mapping of variables between datasets. Joining keys are stored in the join_keys property, which can be set when creating a teal_data object, using the join_keys argument, or using the join_keys function.

ds1 <- data.frame(
  id = seq(1, 10),
  group = rep(c("A", "B"), each = 5)
)
ds2 <- data.frame(
  group = c("A", "B"),
  condition = c("condition1", "condition2")
)
keys <- join_keys(
  join_key("DS1", keys = "id"),
  join_key("DS2", keys = "group"),
  join_key("DS1", "DS2", keys = c("group" = "group"))
)
data_relational1 <- teal_data(DS1 = ds1, DS2 = ds2, join_keys = keys)
data_relational2 <- teal_data(DS1 = ds1, DS2 = ds2)
join_keys(data_relational2) <- keys

For a detailed explanation of join keys, see this teal.data vignette.

(back to ADaM Data)

verified

teal_data allows for tracking code from data creation through data filtering through data analysis so that the whole process can be reproduced. The verified property designates whether or not reproducibility has been confirmed. teal_data objects that are created empty and only modified by evaluating code within them are considered verified by default. Those created with data objects alone or with data objects and code are not verified by default, but can become verified by running the verify function.

data_with_code
#> ✖ unverified teal_data object
#> <environment: 0x55e0536a0518> [L]
#> Parent: <environment: package:ggplot2>
#> Bindings:
#> • cars: <df[,11]> [L]
#> • iris: <df[,5]> [L]

data_with_objects_and_code <- teal_data(iris = iris, cars = mtcars, code = expression(iris <- iris, cars <- mtcars))
data_with_objects_and_code
#> ✖ unverified teal_data object
#> <environment: 0x55e051db5a18> [L]
#> Parent: <environment: package:ggplot2>
#> Bindings:
#> • cars: <df[,11]> [L]
#> • iris: <df[,5]> [L]

data_with_objects_and_code_ver <- verify(data_with_objects_and_code)
data_with_objects_and_code_ver
#> ✅︎ verified teal_data object
#> <environment: 0x55e051db5a18> [L]
#> Parent: <environment: package:ggplot2>
#> Bindings:
#> • cars: <df[,11]> [L]
#> • iris: <df[,5]> [L]

For a detailed explanation of verification, see this teal.data vignette.

(back to Reproducible Data)