Type: Package Package: simIDM Title: Simulating Oncology Trials using an Illness-Death Model Version: 0.1.0.9008 Authors@R: c( person("Alexandra", "Erdmann", , "alexandra.erdmann@uni-ulm.de", role = c("aut", "cre")), person("Kaspar", "Rufibach", , "kaspar.rufibach@roche.com", role = "aut"), person("Holger", "Löwe", , "hbj.loewe@gmail.com", role = "aut"), person("Daniel", "Sabanés Bové", , "daniel.sabanes_bove@roche.com", role = "aut"), person("F. Hoffmann-La Roche AG", role = c("cph", "fnd")), person("University of Ulm", role = c("cph", "fnd")) ) Description: Based on the illness-death model a large number of clinical trials with oncology endpoints progression-free survival (PFS) and overall survival (OS) can be simulated, see Meller, Beyersmann and Rufibach (2019) . The simulation set-up allows for random and event-driven censoring, an arbitrary number of treatment arms, staggered study entry and drop-out. Exponentially, Weibull and piecewise exponentially distributed survival times can be generated. The correlation between PFS and OS can be calculated. License: Apache License 2.0 URL: https://github.com/insightsengineering/simIDM/ BugReports: https://github.com/insightsengineering/simIDM/issues Depends: R (>= 3.6) Imports: checkmate, furrr, future, mstate, parallelly, stats, survival Suggests: coxphw, knitr, mvna, prodlim, rmarkdown, rpact, testthat (>= 3.0.0) VignetteBuilder: knitr Config/testthat/edition: 3 Encoding: UTF-8 Language: en-US Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.2 Repository: https://pharmaverse.r-universe.dev Date/Publication: 2025-02-12 12:57:14 UTC RemoteUrl: https://github.com/insightsengineering/simIDM RemoteRef: HEAD RemoteSha: f3c27cfd5893a27b76a7cf7ef77d12752bbe3d3f NeedsCompilation: no Packaged: 2026-06-06 07:45:06 UTC; root Author: Alexandra Erdmann [aut, cre], Kaspar Rufibach [aut], Holger Löwe [aut], Daniel Sabanés Bové [aut], F. Hoffmann-La Roche AG [cph, fnd], University of Ulm [cph, fnd] Maintainer: Alexandra Erdmann