Type: Package Package: simIDM Title: Simulating Oncology Trials using an Illness-Death Model Version: 0.1.1.9000 Authors@R: c( person("Alexandra", "Erdmann", , "alexandra.erdmann@boehringer-ingelheim.com", role = "aut"), person("Daniel", "Sabanés Bové", , "daniel.sabanes_bove@rconis.com", role = c("aut", "cre")), person("Kaspar", "Rufibach", , "kaspar.rufibach@merckgroup.com", role = "aut"), person("Holger", "Löwe", , "hbj.loewe@gmail.com", role = "aut"), person("F. Hoffmann-La Roche AG", role = c("cph", "fnd")), person("University of Ulm", role = c("cph", "fnd")) ) Description: Based on the illness-death model a large number of clinical trials with oncology endpoints progression-free survival (PFS) and overall survival (OS) can be simulated, see Meller, Beyersmann and Rufibach (2019) . The simulation set-up allows for random and event-driven censoring, an arbitrary number of treatment arms, staggered study entry and drop-out. Exponentially, Weibull and piecewise exponentially distributed survival times can be generated. The correlation between PFS and OS can be calculated. License: Apache License 2.0 URL: https://github.com/insightsengineering/simIDM/ BugReports: https://github.com/insightsengineering/simIDM/issues Depends: R (>= 3.6) Imports: checkmate, furrr, future, mstate, parallelly, stats, survival Suggests: coxphw, knitr, mvna, prodlim, rmarkdown, rpact, testthat (>= 3.0.0) VignetteBuilder: knitr Config/roxygen2/version: 8.0.0 Config/testthat/edition: 3 Encoding: UTF-8 Language: en-US Roxygen: list(markdown = TRUE) Repository: https://pharmaverse.r-universe.dev Date/Publication: 2026-07-08 04:28:41 UTC RemoteUrl: https://github.com/insightsengineering/simIDM RemoteRef: HEAD RemoteSha: fc309b936a8d15919fb266b4512698da7c6e019d NeedsCompilation: no Packaged: 2026-07-08 05:02:20 UTC; root Author: Alexandra Erdmann [aut], Daniel Sabanés Bové [aut, cre], Kaspar Rufibach [aut], Holger Löwe [aut], F. Hoffmann-La Roche AG [cph, fnd], University of Ulm [cph, fnd] Maintainer: Daniel Sabanés Bové