Package: rbmi Title: Reference Based Multiple Imputation Version: 1.6.0.9000 Authors@R: c( person("Lukas A.", "Widmer", email = "lukas_andreas.widmer@novartis.com", role = c("aut", "cre"), comment = c(ORCID = "0000-0003-1471-3493")), person("Craig", "Gower-Page", email = "craig.gower-page@novartis.com", role = c("aut")), person("Isaac", "Gravestock", email = "isaac.gravestock@roche.com", role = c("aut"), comment = c(ORCID = "0000-0003-0283-2065")), person("Alessandro", "Noci", email = "alessandro.noci@roche.com", role = c("aut")), person("Marcel", "Wolbers", email = "marcel.wolbers@roche.com", role = "aut", comment = c(ORCID = "0000-0003-4915-9015")), person("Daniel", "Sabanes Bove", email = "daniel.sabanes_bove@rconis.com", role = c("aut"), comment = c(ORCID = "0000-0002-0176-9239")), person("F. Hoffmann-La Roche AG", role = c("cph", "fnd")) ) Description: Implements standard and reference based multiple imputation methods for continuous longitudinal endpoints (Gower-Page et al. (2022) ). In particular, this package supports deterministic conditional mean imputation and jackknifing as described in Wolbers et al. (2022) , Bayesian multiple imputation as described in Carpenter et al. (2013) , and bootstrapped maximum likelihood imputation as described in von Hippel and Bartlett (2021) . Encoding: UTF-8 LazyData: true Roxygen: list(markdown = TRUE) URL: https://openpharma.github.io/rbmi/, https://github.com/openpharma/rbmi BugReports: https://github.com/openpharma/rbmi/issues RoxygenNote: 7.3.3 Suggests: dplyr, tidyr, nlme, testthat, emmeans, tibble, mvtnorm, knitr, rmarkdown, bookdown, lubridate, purrr, ggplot2, rstan (>= 2.26.0), R.rsp, withr, spelling Config/testthat/edition: 3 Imports: mmrm, pkgload, Matrix, tools, methods, R6, assertthat, jinjar, fs, stringr, lifecycle Depends: R (>= 3.4.0) License: Apache License (>= 2) VignetteBuilder: R.rsp Language: en-GB Config/pak/sysreqs: cmake make libicu-dev libuv1-dev Repository: https://pharmaverse.r-universe.dev Date/Publication: 2026-03-20 19:04:42 UTC RemoteUrl: https://github.com/insightsengineering/rbmi RemoteRef: HEAD RemoteSha: 895e55273bf478eecd3ee516893895aa64eded89 NeedsCompilation: no Packaged: 2026-06-19 14:08:35 UTC; root Author: Lukas A. Widmer [aut, cre] (ORCID: ), Craig Gower-Page [aut], Isaac Gravestock [aut] (ORCID: ), Alessandro Noci [aut], Marcel Wolbers [aut] (ORCID: ), Daniel Sabanes Bove [aut] (ORCID: ), F. Hoffmann-La Roche AG [cph, fnd] Maintainer: Lukas A. Widmer