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"BTOXGR", "R2BASE", "R2ANRLO", "R2ANRHI", "SHIFT1", "SHIFT2", "ANL01FL", "LVOTFL", "TRTP", "TRTA", "ASEQ", "SUBJID", "RFSTDTC", "RFENDTC", "RFXSTDTC", "RFXENDTC", "RFICDTC", "RFPENDTC", "DTHDTC", "DTHFL", "SITEID", "AGE", "AGEU", "SEX", "RACE", "ETHNIC", "ARMCD", "ARM", "ACTARMCD", "ACTARM", "COUNTRY", "DMDTC", "DMDY", "TRTSDTM", "TRTSTMF", "TRTEDTM", "TRTETMF", "TRTDURD", "SCRFDT", "EOSDT", "EOSSTT", "FRVDT", "RANDDT", "DTHDT", "DTHDTF", "DTHADY", "LDDTHELD", "DTHCAUS", "DTHDOM", "DTHCGR1", "LSTALVDT", "SAFFL", "RACEGR1", "AGEGR1", "REGION1", "LDDTHGR1", "DTH30FL", "DTHA30FL", "DTHB30FL" ], "rows": 330, "table": true, "tojson": true }, { "name": "admiral_adsl", "title": "Subject Level Analysis Dataset", "object": "admiral_adsl", "class": [ "tbl_df", "tbl", "data.frame" ], "fields": [ "STUDYID", "USUBJID", "SUBJID", "RFSTDTC", "RFENDTC", "RFXSTDTC", "RFXENDTC", "RFICDTC", "RFPENDTC", "DTHDTC", "DTHFL", "SITEID", "AGE", "AGEU", "SEX", "RACE", "ETHNIC", "ARMCD", "ARM", "ACTARMCD", "ACTARM", "COUNTRY", "DMDTC", "DMDY", "TRT01P", "TRT01A", "TRTSDTM", "TRTSTMF", "TRTEDTM", "TRTETMF", "TRTSDT", "TRTEDT", "TRTDURD", "SCRFDT", "EOSDT", "EOSSTT", "FRVDT", "RANDDT", "DTHDT", "DTHDTF", "DTHADY", "LDDTHELD", "DTHCAUS", "DTHDOM", "DTHCGR1", "LSTALVDT", "SAFFL", "RACEGR1", "AGEGR1", "REGION1", "LDDTHGR1", "DTH30FL", "DTHA30FL", "DTHB30FL" ], "rows": 306, "table": true, "tojson": true }, { "name": "atoxgr_criteria_ctcv4", "title": "Metadata Holding Grading Criteria for NCI-CTCAEv4 using SI unit where applicable", "object": "atoxgr_criteria_ctcv4", "class": [ "data.frame" ], "fields": [ "SOC", "TERM", "GRADE_1", "GRADE_2", "GRADE_3", "GRADE_4", "GRADE_5", "Definition", "UNIT_CHECK", "VAR_CHECK", "DIRECTION", "COMMENT", "GRADE_CRITERIA_CODE" ], "rows": 42, "table": true, "tojson": true }, { "name": "atoxgr_criteria_ctcv4_uscv", "title": "Metadata Holding Grading Criteria for NCI-CTCAEv4 using USCV unit where applicable", "object": "atoxgr_criteria_ctcv4_uscv", "class": [ "data.frame" ], "fields": [ "SOC", "TERM", "GRADE_1", "GRADE_2", "GRADE_3", "GRADE_4", "GRADE_5", "Definition", "UNIT_CHECK", "VAR_CHECK", "DIRECTION", "COMMENT", "GRADE_CRITERIA_CODE" ], "rows": 48, "table": true, "tojson": true }, { "name": "atoxgr_criteria_ctcv5", "title": "Metadata Holding Grading Criteria for NCI-CTCAEv5 using SI unit where applicable", "object": "atoxgr_criteria_ctcv5", "class": [ "data.frame" ], "fields": [ "SOC", "TERM", "GRADE_1", "GRADE_2", "GRADE_3", "GRADE_4", "GRADE_5", "Definition", "UNIT_CHECK", "VAR_CHECK", "DIRECTION", "COMMENT", "GRADE_CRITERIA_CODE" ], "rows": 40, "table": true, "tojson": true }, { "name": "atoxgr_criteria_ctcv5_uscv", "title": "Metadata Holding Grading Criteria for NCI-CTCAEv5 using USCV unit where applicable", "object": "atoxgr_criteria_ctcv5_uscv", "class": [ "data.frame" ], "fields": [ "SOC", "TERM", "GRADE_1", "GRADE_2", "GRADE_3", "GRADE_4", "GRADE_5", "Definition", "UNIT_CHECK", "VAR_CHECK", "DIRECTION", "COMMENT", "GRADE_CRITERIA_CODE" ], "rows": 46, "table": true, "tojson": true }, { "name": "atoxgr_criteria_ctcv6", "title": "Metadata Holding Grading Criteria for NCI-CTCAEv6 using SI unit where applicable", "object": "atoxgr_criteria_ctcv6", "class": [ "data.frame" ], "fields": [ "SOC", "TERM", "GRADE_1", "GRADE_2", "GRADE_3", "GRADE_4", "GRADE_5", "Definition", "UNIT_CHECK", "VAR_CHECK", "DIRECTION", "COMMENT", "GRADE_CRITERIA_CODE" ], "rows": 43, "table": true, "tojson": true }, { "name": "atoxgr_criteria_ctcv6_uscv", "title": "Metadata Holding Grading Criteria for NCI-CTCAEv6 using USCV unit where applicable", "object": "atoxgr_criteria_ctcv6_uscv", "class": [ "data.frame" ], "fields": [ "SOC", "TERM", "GRADE_1", "GRADE_2", "GRADE_3", "GRADE_4", "GRADE_5", "Definition", "UNIT_CHECK", "VAR_CHECK", "DIRECTION", "COMMENT", "GRADE_CRITERIA_CODE" ], "rows": 48, "table": true, "tojson": true }, { "name": "atoxgr_criteria_daids", "title": "Metadata Holding Grading Criteria for DAIDs using SI unit where applicable", "object": "atoxgr_criteria_daids", "class": [ "data.frame" ], "fields": [ "SOC", "TERM", "GRADE_2", "GRADE_3", "GRADE_4", "VAR_CHECK", "DIRECTION", "COMMENT", "GRADE_1", "UNIT_CHECK", "SUBGROUP", "FILTER", "GRADE_5", "GRADE_CRITERIA_CODE" ], "rows": 63, "table": true, "tojson": true }, { "name": "atoxgr_criteria_daids_uscv", "title": "Metadata Holding Grading Criteria for DAIDs using USCV unit where applicable", "object": "atoxgr_criteria_daids_uscv", "class": [ "data.frame" ], "fields": [ "SOC", "TERM", "GRADE_2", "GRADE_3", "GRADE_4", "VAR_CHECK", "DIRECTION", "COMMENT", "GRADE_1", "UNIT_CHECK", "SUBGROUP", "FILTER", "GRADE_5", "GRADE_CRITERIA_CODE" ], "rows": 71, "table": true, "tojson": true }, { "name": "country_code_lookup", "title": "Country Code Lookup", "object": "country_code_lookup", "class": [ "tbl_df", "tbl", "data.frame" ], "fields": [ "country_code", "country_name", "country_number" ], "rows": 249, "table": true, "tojson": true }, { "name": "dose_freq_lookup", "title": "Pre-Defined Dose Frequencies", "object": "dose_freq_lookup", "class": [ "tbl_df", "tbl", "data.frame" ], "fields": [ "NCI_CODE", "CDISC_VALUE", "DOSE_COUNT", "DOSE_WINDOW", "CONVERSION_FACTOR" ], "rows": 86, "table": true, "tojson": true }, { "name": "example_qs", "title": "Example 'QS' Dataset", "object": "example_qs", "class": [ "tbl_df", "tbl", "data.frame" ], "fields": [ "STUDYID", "USUBJID", "QSSEQ", "QSTESTCD", "QSTEST", "VISIT", "VISITNUM", "QSDTC", "QSORRES", "QSCAT", "QSSTRESN" ], "rows": 161, "table": true, "tojson": true }, { "name": "queries", "title": "Queries Dataset", "object": "queries", "class": [ "tbl_df", "tbl", "data.frame" ], "fields": [ "PREFIX", "GRPNAME", "GRPID", "SCOPE", "SCOPEN", "SRCVAR", "TERMCHAR", "TERMNUM" ], "rows": 15, "table": true, "tojson": true }, { "name": "queries_mh", "title": "Queries MH Dataset", "object": "queries_mh", "class": [ "tbl_df", "tbl", "data.frame" ], "fields": [ "PREFIX", "GRPNAME", "GRPID", "SCOPE", "SCOPEN", "SRCVAR", "TERMCHAR", "TERMNUM" ], "rows": 14, "table": true, "tojson": true } ], "_help": [ { "page": "pipe", "title": "Pipe operator", "topics": [ "%>%" ] }, { "page": "admiral_adlb", "title": "Lab Analysis Dataset", "concept": [ "datasets" ], "topics": [ "admiral_adlb" ] }, { "page": "admiral_adsl", "title": "Subject Level Analysis Dataset", "concept": [ "datasets" ], "topics": [ "admiral_adsl" ] }, { "page": "atoxgr_criteria_ctcv4", "title": "Metadata Holding Grading Criteria for NCI-CTCAEv4 using SI unit where applicable", "concept": [ "metadata" ], "topics": [ "atoxgr_criteria_ctcv4" ] }, { "page": "atoxgr_criteria_ctcv4_uscv", "title": "Metadata Holding Grading Criteria for NCI-CTCAEv4 using USCV unit where applicable", "concept": [ "metadata" ], "topics": [ "atoxgr_criteria_ctcv4_uscv" ] }, { "page": "atoxgr_criteria_ctcv5", "title": "Metadata Holding Grading Criteria for NCI-CTCAEv5 using SI unit where applicable", "concept": [ "metadata" ], "topics": [ "atoxgr_criteria_ctcv5" ] }, { "page": "atoxgr_criteria_ctcv5_uscv", "title": "Metadata Holding Grading Criteria for NCI-CTCAEv5 using USCV unit where applicable", "concept": [ "metadata" ], "topics": [ "atoxgr_criteria_ctcv5_uscv" ] }, { "page": "atoxgr_criteria_ctcv6", "title": "Metadata Holding Grading Criteria for NCI-CTCAEv6 using SI unit where applicable", "concept": [ "metadata" ], "topics": [ "atoxgr_criteria_ctcv6" ] }, { "page": "atoxgr_criteria_ctcv6_uscv", "title": "Metadata Holding Grading Criteria for NCI-CTCAEv6 using USCV unit where applicable", "concept": [ "metadata" ], "topics": [ "atoxgr_criteria_ctcv6_uscv" ] }, { "page": "atoxgr_criteria_daids", "title": "Metadata Holding Grading Criteria for DAIDs using SI unit where applicable", "concept": [ "metadata" ], "topics": [ "atoxgr_criteria_daids" ] }, { "page": "atoxgr_criteria_daids_uscv", "title": "Metadata Holding Grading Criteria for DAIDs using USCV unit where applicable", "concept": [ "metadata" ], "topics": [ "atoxgr_criteria_daids_uscv" ] }, { "page": "basket_select", "title": "Create a 'basket_select' object", "concept": [ "source_specifications" ], "topics": [ "basket_select" ] }, { "page": "call_derivation", "title": "Call a Single Derivation Multiple Times", "concept": [ "high_order_function" ], "topics": [ "call_derivation" ] }, { "page": "call_user_fun", "title": "Calls a Function Provided by the User", "concept": [ "deprecated" ], "topics": [ "call_user_fun" ] }, { "page": "censor_source", "title": "Create a 'censor_source' Object", "concept": [ "source_specifications" ], "topics": [ "censor_source" ] }, { "page": "chr2vars", "title": "Turn a Character Vector into a List of Expressions", "concept": [ "utils_quo" ], "topics": [ "chr2vars" ] }, { "page": "compute_age_years", "title": "Compute Age in Years", "concept": [ "com_date_time" ], "topics": [ "compute_age_years" ] }, { "page": "compute_bmi", "title": "Compute Body Mass Index (BMI)", "concept": [ "com_bds_findings" ], "topics": [ "compute_bmi" ] }, { "page": "compute_bsa", "title": "Compute Body Surface Area (BSA)", "concept": [ "com_bds_findings" ], "topics": [ "compute_bsa" ] }, { "page": "compute_dtf", "title": "Derive the Date Imputation Flag", "concept": [ "com_date_time" ], "topics": [ "compute_dtf" ] }, { "page": "compute_duration", "title": "Compute Duration", "concept": [ "com_date_time" ], "topics": [ "compute_duration" ] }, { "page": "compute_egfr", "title": "Compute Estimated Glomerular Filtration Rate (eGFR) for Kidney Function", "concept": [ "com_bds_findings" ], "topics": [ "compute_egfr" ] }, { "page": "compute_framingham", "title": "Compute Framingham Heart Study Cardiovascular Disease 10-Year Risk Score", "concept": [ "com_bds_findings" ], "topics": [ "compute_framingham" ] }, { "page": "compute_map", "title": "Compute Mean Arterial Pressure (MAP)", "concept": [ "com_bds_findings" ], "topics": [ "compute_map" ] }, { "page": "compute_qtc", "title": "Compute Corrected QT", "concept": [ "com_bds_findings" ], "topics": [ "compute_qtc" ] }, { "page": "compute_qual_imputation", "title": "Function to Impute Values When Qualifier Exists in Character Result", "concept": [ "com_bds_findings" ], "topics": [ "compute_qual_imputation" ] }, { "page": "compute_qual_imputation_dec", "title": "Compute Factor for Value Imputations When Character Value Contains < or >", "concept": [ "com_bds_findings" ], "topics": [ "compute_qual_imputation_dec" ] }, { "page": "compute_rr", "title": "Compute RR Interval From Heart Rate", "concept": [ "com_bds_findings" ], "topics": [ "compute_rr" ] }, { "page": "compute_scale", "title": "Compute Scale Parameters", "concept": [ "com_bds_findings" ], "topics": [ "compute_scale" ] }, { "page": "compute_tmf", "title": "Derive the Time Imputation Flag", "concept": [ "com_date_time" ], "topics": [ "compute_tmf" ] }, { "page": "consolidate_metadata", "title": "Consolidate Multiple Meta Datasets Into a Single One", "concept": [ "create_aux" ], "topics": [ "consolidate_metadata" ] }, { "page": "convert_blanks_to_na", "title": "Convert Blank Strings Into NAs", "concept": [ "utils_fmt" ], "topics": [ "convert_blanks_to_na", "convert_blanks_to_na.character", "convert_blanks_to_na.data.frame", "convert_blanks_to_na.default", "convert_blanks_to_na.list" ] }, { "page": "convert_date_to_dtm", "title": "Convert a Date into a Datetime Object", "concept": [ "com_date_time" ], "topics": [ "convert_date_to_dtm" ] }, { "page": "convert_dtc_to_dt", "title": "Convert a Date Character Vector into a Date Object", "concept": [ "com_date_time" ], "topics": [ "convert_dtc_to_dt" ] }, { "page": "convert_dtc_to_dtm", "title": "Convert a Date Character Vector into a Datetime Object", "concept": [ "com_date_time" ], "topics": [ "convert_dtc_to_dtm" ] }, { "page": "convert_na_to_blanks", "title": "Convert NAs Into Blank Strings", "concept": [ "utils_fmt" ], "topics": [ "convert_na_to_blanks", "convert_na_to_blanks.character", "convert_na_to_blanks.data.frame", "convert_na_to_blanks.default", "convert_na_to_blanks.list" ] }, { "page": "convert_xxtpt_to_hours", "title": "Convert 'XXTPT' Strings to Hours", "concept": [ "com_date_time" ], "topics": [ "convert_xxtpt_to_hours" ] }, { "page": "count_vals", "title": "Count Number of Observations Where a Variable Equals a Value", "concept": [ "utils_fil" ], "topics": [ "count_vals" ] }, { "page": "country_code_lookup", "title": "Country Code Lookup", "concept": [ "metadata" ], "topics": [ "country_code_lookup" ] }, { "page": "create_period_dataset", "title": "Create a Reference Dataset for Subperiods, Periods, or Phases", "concept": [ "create_aux" ], "topics": [ "create_period_dataset" ] }, { "page": "create_query_data", "title": "Creates a queries dataset as input dataset to the 'dataset_queries' argument in 'derive_vars_query()'", "concept": [ "create_aux" ], "topics": [ "create_query_data" ] }, { "page": "create_single_dose_dataset", "title": "Create dataset of single doses", "concept": [ "create_aux" ], "topics": [ "create_single_dose_dataset" ] }, { "page": "date_source", "title": "Create a 'date_source' object", "concept": [ "deprecated" ], "topics": [ "date_source" ] }, { "page": "tte_source_objects", "title": "Pre-Defined Time-to-Event Source Objects", "concept": [ "source_specifications" ], "topics": [ "ae_event", "ae_gr1_event", "ae_gr2_event", "ae_gr35_event", "ae_gr3_event", "ae_gr4_event", "ae_gr5_event", "ae_ser_event", "ae_sev_event", "ae_wd_event", "death_event", "lastalive_censor" ] }, { "page": "default_qtc_paramcd", "title": "Get Default Parameter Code for Corrected QT", "concept": [ "der_prm_bds_findings" ], "topics": [ "default_qtc_paramcd" ] }, { "page": "derivation_slice", "title": "Create a 'derivation_slice' Object", "concept": [ "high_order_function" ], "topics": [ "derivation_slice" ] }, { "page": "derive_basetype_records", "title": "Derive Basetype Variable", "concept": [ "der_prm_bds_findings" ], "topics": [ "derive_basetype_records" ] }, { "page": "derive_expected_records", "title": "Derive Expected Records", "concept": [ "der_prm_bds_findings" ], "topics": [ "derive_expected_records" ] }, { "page": "derive_extreme_event", "title": "Add the Worst or Best Observation for Each By Group as New Records", "concept": [ "der_prm_bds_findings" ], "topics": [ "derive_extreme_event" ] }, { "page": "derive_extreme_records", "title": "Add the First or Last Observation for Each By Group as New Records", "concept": [ "der_prm_bds_findings" ], "topics": [ "derive_extreme_records" ] }, { "page": "derive_locf_records", "title": "Derive LOCF (Last Observation Carried Forward) Records", "concept": [ "der_prm_bds_findings" ], "topics": [ "derive_locf_records" ] }, { "page": "derive_param_bmi", "title": "Adds a Parameter for BMI", "concept": [ "der_prm_bds_findings" ], "topics": [ "derive_param_bmi" ] }, { "page": "derive_param_bsa", "title": "Adds a Parameter for BSA (Body Surface Area) Using the Specified Method", "concept": [ "der_prm_bds_findings" ], "topics": [ "derive_param_bsa" ] }, { "page": "derive_param_computed", "title": "Adds a Parameter Computed from the Analysis Value of Other Parameters", "concept": [ "der_prm_bds_findings" ], "topics": [ "derive_param_computed" ] }, { "page": "derive_param_doseint", "title": "Adds a Parameter for Dose Intensity", "concept": [ "der_prm_bds_findings" ], "topics": [ "derive_param_doseint" ] }, { "page": "derive_param_exist_flag", "title": "Add an Existence Flag Parameter", "concept": [ "der_prm_bds_findings" ], "topics": [ "derive_param_exist_flag" ] }, { "page": "derive_param_exposure", "title": "Add an Aggregated Parameter and Derive the Associated Start and End Dates", "concept": [ "der_prm_bds_findings" ], "topics": [ "derive_param_exposure" ] }, { "page": "derive_param_extreme_record", "title": "Adds a Parameter Based on First or Last Record from Multiple Sources", "concept": [ "deprecated" ], "topics": [ "derive_param_extreme_record" ] }, { "page": "derive_param_framingham", "title": "Adds a Parameter for Framingham Heart Study Cardiovascular Disease 10-Year Risk Score", "concept": [ "der_prm_bds_findings" ], "topics": [ "derive_param_framingham" ] }, { "page": "derive_param_map", "title": "Adds a Parameter for Mean Arterial Pressure", "concept": [ "der_prm_bds_findings" ], "topics": [ "derive_param_map" ] }, { "page": "derive_param_qtc", "title": "Adds a Parameter for Corrected QT (an ECG measurement)", "concept": [ "der_prm_bds_findings" ], "topics": [ "derive_param_qtc" ] }, { "page": "derive_param_rr", "title": "Adds a Parameter for Derived RR (an ECG measurement)", "concept": [ "der_prm_bds_findings" ], "topics": [ "derive_param_rr" ] }, { "page": "derive_param_tte", "title": "Derive a Time-to-Event Parameter", "concept": [ "der_prm_tte" ], "topics": [ "derive_param_tte" ] }, { "page": "derive_param_wbc_abs", "title": "Add a parameter for lab differentials converted to absolute values", "concept": [ "der_prm_bds_findings" ], "topics": [ "derive_param_wbc_abs" ] }, { "page": "derive_summary_records", "title": "Add New Records Within By Groups Using Aggregation Functions", "concept": [ "der_prm_bds_findings" ], "topics": [ "derive_summary_records" ] }, { "page": "derive_var_age_years", "title": "Derive Age in Years", "concept": [ "der_adsl" ], "topics": [ "derive_var_age_years" ] }, { "page": "derive_var_analysis_ratio", "title": "Derive Ratio Variable", "concept": [ "der_bds_findings" ], "topics": [ "derive_var_analysis_ratio" ] }, { "page": "derive_var_anrind", "title": "Derive Reference Range Indicator", "concept": [ "der_bds_findings" ], "topics": [ "derive_var_anrind" ] }, { "page": "derive_var_atoxgr", "title": "Derive Lab High toxicity Grade 0 - 4 and Low Toxicity Grades 0 - (-4)", "concept": [ "der_bds_findings" ], "topics": [ "derive_var_atoxgr" ] }, { "page": "derive_var_atoxgr_dir", "title": "Derive Lab Toxicity Grade 0 - 4", "concept": [ "der_bds_findings" ], "topics": [ "derive_var_atoxgr_dir" ] }, { "page": "derive_var_base", "title": "Derive Baseline Variables", "concept": [ "der_bds_findings" ], "topics": [ "derive_var_base" ] }, { "page": "derive_var_chg", "title": "Derive Change from Baseline", "concept": [ "der_bds_findings" ], "topics": [ "derive_var_chg" ] }, { "page": "derive_var_dthcaus", "title": "Derive Death Cause", "concept": [ "deprecated" ], "topics": [ "derive_var_dthcaus" ] }, { "page": "derive_var_extreme_dt", "title": "Derive First or Last Date from Multiple Sources", "concept": [ "deprecated" ], "topics": [ "derive_var_extreme_dt" ] }, { "page": "derive_var_extreme_dtm", "title": "Derive First or Last Datetime from Multiple Sources", "concept": [ "deprecated" ], "topics": [ "derive_var_extreme_dtm" ] }, { "page": "derive_var_extreme_flag", "title": "Add a Variable Flagging the First or Last Observation Within Each By Group", "concept": [ "der_gen" ], "topics": [ "derive_var_extreme_flag" ] }, { "page": "derive_var_joined_exist_flag", "title": "Derives a 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