| Title: | Pediatrics Extension Package for ADaM in 'R' Asset Library |
|---|---|
| Description: | A toolbox for programming Clinical Data Standards Interchange Consortium (CDISC) compliant Analysis Data Model (ADaM) datasets in R. ADaM datasets are a mandatory part of any New Drug or Biologics License Application submitted to the United States Food and Drug Administration (FDA). Analysis derivations are implemented in accordance with the "Analysis Data Model Implementation Guide" (CDISC Analysis Data Model Team, 2021, <https://www.cdisc.org/standards/foundational/adam>). The package is an extension package of the 'admiral' package for pediatric clinical trials. |
| Authors: | Fanny Gautier [aut, cre] (ORCID: <https://orcid.org/0009-0004-3581-0131>), Ross Farrugia [aut], Zelos Zhu [aut], Sukalpo Saha [aut], Lina Patil [aut], Samia Kabi [aut], Laura Liao [ctb], Remigiusz Kudlacz [ctb], Pierre Wallet [ctb], Amin Sherzad [ctb], David Freedman [ctb], Mahmoud Hamza [ctb], Cytel Inc. [cph, fnd], F. Hoffmann-La Roche AG [cph, fnd], Pfizer Inc. [cph, fnd], Atorus Research [cph, fnd] |
| Maintainer: | Fanny Gautier <[email protected]> |
| License: | Apache License (>= 2) |
| Version: | 0.4.0.9000 |
| Built: | 2026-10-12 16:15:18 UTC |
| Source: | https://github.com/pharmaverse/admiralpeds |
An updated ADaM ADSL dataset with pediatric patients
adsl_pedsadsl_peds
An object of class tbl_df (inherits from tbl, data.frame) with 5 rows and 35 columns.
BMI-for-age charts, 2 to 20.5 years
cdc_bmiagecdc_bmiage
A data frame with 438 rows and 7 variables:
SEXSex: 1 = male, 2 = female
AGEAge in months
LBox-Cox transformation for normality
MMedian
SCoefficient of variation
SigmaSigma
P9595th Percentile
https://www.cdc.gov/growthcharts/percentile_data_files.htm
Metadata:
cdc_htage,
cdc_wtage,
derive_interp_records(),
who_bmi_for_age_boys,
who_bmi_for_age_girls,
who_hc_for_age_boys,
who_hc_for_age_girls,
who_lgth_ht_for_age_boys,
who_lgth_ht_for_age_girls,
who_wt_for_age_boys,
who_wt_for_age_girls,
who_wt_for_lgth_boys,
who_wt_for_lgth_girls
Height-for-age charts, 2 to 20 years
cdc_htagecdc_htage
A data frame with 436 rows and 5 variables:
SEXSex: 1 = male, 2 = female
AGEAge in months
LBox-Cox transformation for normality
MMedian
SCoefficient of variation
https://www.cdc.gov/growthcharts/percentile_data_files.htm
Metadata:
cdc_bmiage,
cdc_wtage,
derive_interp_records(),
who_bmi_for_age_boys,
who_bmi_for_age_girls,
who_hc_for_age_boys,
who_hc_for_age_girls,
who_lgth_ht_for_age_boys,
who_lgth_ht_for_age_girls,
who_wt_for_age_boys,
who_wt_for_age_girls,
who_wt_for_lgth_boys,
who_wt_for_lgth_girls
Weight-for-age charts, 2 to 20 years
cdc_wtagecdc_wtage
A data frame with 436 rows and 5 variables:
SEXSex: 1 = male, 2 = female
AGEAge in months
LBox-Cox transformation for normality
MMedian
SCoefficient of variation
https://www.cdc.gov/growthcharts/percentile_data_files.htm
Metadata:
cdc_bmiage,
cdc_htage,
derive_interp_records(),
who_bmi_for_age_boys,
who_bmi_for_age_girls,
who_hc_for_age_boys,
who_hc_for_age_girls,
who_lgth_ht_for_age_boys,
who_lgth_ht_for_age_girls,
who_wt_for_age_boys,
who_wt_for_age_girls,
who_wt_for_lgth_boys,
who_wt_for_lgth_girls
Derive a linear interpolation of rows for the CDC charts (>=2 yrs old) by age in days for the following parameters: HEIGHT, WEIGHT and BMI
derive_interp_records(dataset, by_vars = NULL, parameter)derive_interp_records(dataset, by_vars = NULL, parameter)
dataset |
Input metadataset The variables For BMI the additional variables Note that
|
by_vars |
Grouping variables The variable from
|
parameter |
CDC/WHO metadata parameter
|
The input dataset plus additional interpolated records: a record for each day from the minimum age to the maximum age.
If any variables in addition to the expected ones are in the input dataset, LOCF (Last Observation Carried Forward) is applied to populate them for the new records.
Metadata:
cdc_bmiage,
cdc_htage,
cdc_wtage,
who_bmi_for_age_boys,
who_bmi_for_age_girls,
who_hc_for_age_boys,
who_hc_for_age_girls,
who_lgth_ht_for_age_boys,
who_lgth_ht_for_age_girls,
who_wt_for_age_boys,
who_wt_for_age_girls,
who_wt_for_lgth_boys,
who_wt_for_lgth_girls
library(dplyr, warn.conflicts = FALSE) library(rlang, warn.conflicts = FALSE) cdc_htage <- admiralpeds::cdc_htage %>% mutate( SEX = case_when( SEX == 1 ~ "M", SEX == 2 ~ "F", TRUE ~ NA_character_ ), # Ensure first that Age unit is "DAYS" AGE = round(AGE * 30.4375), AGEU = "DAYS" ) # Interpolate the AGE by SEX derive_interp_records( dataset = cdc_htage, by_vars = exprs(SEX), parameter = "HEIGHT" )library(dplyr, warn.conflicts = FALSE) library(rlang, warn.conflicts = FALSE) cdc_htage <- admiralpeds::cdc_htage %>% mutate( SEX = case_when( SEX == 1 ~ "M", SEX == 2 ~ "F", TRUE ~ NA_character_ ), # Ensure first that Age unit is "DAYS" AGE = round(AGE * 30.4375), AGEU = "DAYS" ) # Interpolate the AGE by SEX derive_interp_records( dataset = cdc_htage, by_vars = exprs(SEX), parameter = "HEIGHT" )
Derive Anthropometric indicators (Z-Scores/Percentiles-for-Age) based on Standard Growth Charts for Height/Weight/BMI/Head Circumference by Age
derive_params_growth_age( dataset, sex, age, age_unit, meta_criteria, parameter, analysis_var, bmi_cdc_correction = FALSE, who_correction = FALSE, set_values_to_sds = NULL, set_values_to_pctl = NULL )derive_params_growth_age( dataset, sex, age, age_unit, meta_criteria, parameter, analysis_var, bmi_cdc_correction = FALSE, who_correction = FALSE, set_values_to_sds = NULL, set_values_to_pctl = NULL )
dataset |
Input dataset The variables specified in
|
sex |
Sex
|
age |
Current Age
|
age_unit |
Age Unit
|
meta_criteria |
Metadata dataset A metadata dataset with the following expected variables:
The dataset can be derived from CDC/WHO or user-defined datasets. The CDC/WHO growth chart metadata datasets are available in the package and will require small modifications. If the
|
parameter |
Anthropometric measurement parameter to calculate z-score or percentile A condition is expected with the input dataset e.g. There is CDC/WHO metadata available for Height, Weight, BMI, and Head Circumference available
in the
|
analysis_var |
Variable containing anthropometric measurement
|
bmi_cdc_correction |
Extended CDC BMI-for-age correction CDC developed extended percentiles (>95%) to monitor high BMI values,
if set to
|
who_correction |
WHO adjustment for weight-based indicators WHO constructed a restricted application of the LMS method for weight-based indicators.
More details on these exact rules applied can be found at the document page 302 of the
WHO Child Growth Standards Guidelines.
If set to
|
set_values_to_sds |
Variables to be set for Z-Scores The specified variables are set to the specified values for the new
observations. For example,
The formula to calculate the Z-score is as follows:
where "obs" is the observed value for the respective anthropometric measure being calculated.
|
set_values_to_pctl |
Variables to be set for Percentile The specified variables are set to the specified values for the new
observations. For example,
|
This function requires that the age unit (age_unit parameter) in the input dataset
matches the age unit (AGEU variable) in the metadata (meta_criteria). The function
does NOT perform automatic age unit conversion.
If records from the input dataset cannot be matched to the metadata due to:
Mismatched age units (e.g., data in days but metadata in months)
Missing metadata for the specific age/sex combination
a warning (as shown in the example below) will be issued, listing the number of unmatched records. These records will NOT appear in the output dataset.
To resolve age unit mismatches, standardize your data before calling this function.
The input dataset additional records with the new parameter added.
Vital Signs Functions for adding Parameters/Records:
derive_params_growth_height()
library(dplyr, warn.conflicts = FALSE) library(lubridate, warn.conflicts = FALSE) library(rlang, warn.conflicts = FALSE) library(admiral, warn.conflicts = FALSE) library(pharmaversesdtm, warn.conflicts = FALSE) advs <- pharmaversesdtm::dm_peds %>% select(USUBJID, BRTHDTC, SEX) %>% right_join(., pharmaversesdtm::vs_peds, by = "USUBJID") %>% mutate( VSDT = ymd(VSDTC), BRTHDT = ymd(BRTHDTC) ) %>% derive_vars_duration( new_var = AGECUR_D, new_var_unit = CURU_D, start_date = BRTHDT, end_date = VSDT, out_unit = "days", trunc_out = FALSE ) %>% derive_vars_duration( new_var = AGECUR_M, new_var_unit = CURU_M, start_date = BRTHDT, end_date = VSDT, out_unit = "months", trunc_out = FALSE ) %>% mutate( AGECUR = if_else(AGECUR_D >= 365.25 * 2, AGECUR_M, AGECUR_D), AGECURU = if_else(AGECUR_D >= 365.25 * 2, CURU_M, CURU_D) ) # metadata is in months cdc_meta_criteria <- admiralpeds::cdc_htage %>% mutate( age_unit = "months", SEX = if_else(SEX == 1, "M", "F") ) # metadata is in days who_meta_criteria <- bind_rows( (admiralpeds::who_lgth_ht_for_age_boys %>% mutate( SEX = "M", age_unit = "days" ) ), (admiralpeds::who_lgth_ht_for_age_girls %>% mutate( SEX = "F", age_unit = "days" ) ) ) %>% rename(AGE = Day) criteria <- bind_rows( cdc_meta_criteria, who_meta_criteria ) %>% rename(AGEU = age_unit) derive_params_growth_age( advs, sex = SEX, age = AGECUR, age_unit = AGECURU, meta_criteria = criteria, parameter = VSTESTCD == "HEIGHT", analysis_var = VSSTRESN, set_values_to_sds = exprs( PARAMCD = "HGTSDS", PARAM = "Height-for-age z-score" ), set_values_to_pctl = exprs( PARAMCD = "HGTPCTL", PARAM = "Height-for-age percentile" ) )library(dplyr, warn.conflicts = FALSE) library(lubridate, warn.conflicts = FALSE) library(rlang, warn.conflicts = FALSE) library(admiral, warn.conflicts = FALSE) library(pharmaversesdtm, warn.conflicts = FALSE) advs <- pharmaversesdtm::dm_peds %>% select(USUBJID, BRTHDTC, SEX) %>% right_join(., pharmaversesdtm::vs_peds, by = "USUBJID") %>% mutate( VSDT = ymd(VSDTC), BRTHDT = ymd(BRTHDTC) ) %>% derive_vars_duration( new_var = AGECUR_D, new_var_unit = CURU_D, start_date = BRTHDT, end_date = VSDT, out_unit = "days", trunc_out = FALSE ) %>% derive_vars_duration( new_var = AGECUR_M, new_var_unit = CURU_M, start_date = BRTHDT, end_date = VSDT, out_unit = "months", trunc_out = FALSE ) %>% mutate( AGECUR = if_else(AGECUR_D >= 365.25 * 2, AGECUR_M, AGECUR_D), AGECURU = if_else(AGECUR_D >= 365.25 * 2, CURU_M, CURU_D) ) # metadata is in months cdc_meta_criteria <- admiralpeds::cdc_htage %>% mutate( age_unit = "months", SEX = if_else(SEX == 1, "M", "F") ) # metadata is in days who_meta_criteria <- bind_rows( (admiralpeds::who_lgth_ht_for_age_boys %>% mutate( SEX = "M", age_unit = "days" ) ), (admiralpeds::who_lgth_ht_for_age_girls %>% mutate( SEX = "F", age_unit = "days" ) ) ) %>% rename(AGE = Day) criteria <- bind_rows( cdc_meta_criteria, who_meta_criteria ) %>% rename(AGEU = age_unit) derive_params_growth_age( advs, sex = SEX, age = AGECUR, age_unit = AGECURU, meta_criteria = criteria, parameter = VSTESTCD == "HEIGHT", analysis_var = VSSTRESN, set_values_to_sds = exprs( PARAMCD = "HGTSDS", PARAM = "Height-for-age z-score" ), set_values_to_pctl = exprs( PARAMCD = "HGTPCTL", PARAM = "Height-for-age percentile" ) )
Derive Anthropometric indicators (Z-Scores/Percentiles-for-Height/Length) based on Standard Growth Charts for Weight by Height/Length
derive_params_growth_height( dataset, sex, height, height_unit, meta_criteria, parameter, analysis_var, who_correction = FALSE, set_values_to_sds = NULL, set_values_to_pctl = NULL )derive_params_growth_height( dataset, sex, height, height_unit, meta_criteria, parameter, analysis_var, who_correction = FALSE, set_values_to_sds = NULL, set_values_to_pctl = NULL )
dataset |
Input dataset The variables specified in
|
sex |
Sex
|
height |
Current Height/length
|
height_unit |
Height/Length Unit
|
meta_criteria |
Metadata dataset A metadata dataset with the following expected variables:
The dataset can be derived from WHO or user-defined datasets. The WHO growth chart metadata datasets are available in the package and will require small modifications. Datasets If the
|
parameter |
Anthropometric measurement parameter to calculate z-score or percentile A condition is expected with the input dataset e.g. There is WHO metadata available for Weight available in the
|
analysis_var |
Variable containing anthropometric measurement
|
who_correction |
WHO adjustment for weight-based indicators WHO constructed a restricted application of the LMS method for weight-based indicators.
More details on these exact rules applied can be found at the document page 302 of the
WHO Child Growth Standards Guidelines.
If set to
|
set_values_to_sds |
Variables to be set for Z-Scores The specified variables are set to the specified values for the new
observations. For example,
The formula to calculate the Z-score is as follows:
where "obs" is the observed value for the respective anthropometric measure being calculated.
|
set_values_to_pctl |
Variables to be set for Percentile The specified variables are set to the specified values for the new
observations. For example,
|
The input dataset additional records with the new parameter added.
Vital Signs Functions for adding Parameters/Records:
derive_params_growth_age()
library(dplyr, warn.conflicts = FALSE) library(lubridate, warn.conflicts = FALSE) library(rlang, warn.conflicts = FALSE) library(admiral, warn.conflicts = FALSE) library(pharmaversesdtm, warn.conflicts = FALSE) # derive weight for height/length only for those under 2 years old using WHO # weight for length reference file advs <- pharmaversesdtm::dm_peds %>% select(USUBJID, BRTHDTC, SEX) %>% right_join(., pharmaversesdtm::vs_peds, by = "USUBJID") %>% mutate( VSDT = ymd(VSDTC), BRTHDT = ymd(BRTHDTC) ) %>% derive_vars_duration( new_var = AAGECUR, new_var_unit = AAGECURU, start_date = BRTHDT, end_date = VSDT, out_unit = "days" ) heights <- pharmaversesdtm::vs_peds %>% filter(VSTESTCD == "HEIGHT") %>% select(USUBJID, VSSTRESN, VSSTRESU, VSDTC) %>% rename( HGTTMP = VSSTRESN, HGTTMPU = VSSTRESU ) advs <- advs %>% right_join(., heights, by = c("USUBJID", "VSDTC")) advs_under2 <- advs %>% filter(AAGECUR < 730.5) who_under2 <- bind_rows( (admiralpeds::who_wt_for_lgth_boys %>% mutate( SEX = "M", height_unit = "cm" ) ), (admiralpeds::who_wt_for_lgth_girls %>% mutate( SEX = "F", height_unit = "cm" ) ) ) %>% rename( HEIGHT_LENGTH = Length, HEIGHT_LENGTHU = height_unit ) derive_params_growth_height( advs_under2, sex = SEX, height = HGTTMP, height_unit = HGTTMPU, meta_criteria = who_under2, parameter = VSTESTCD == "WEIGHT", analysis_var = VSSTRESN, who_correction = TRUE, set_values_to_sds = exprs( PARAMCD = "WGTHSDS", PARAM = "Weight-for-height/length z-score" ), set_values_to_pctl = exprs( PARAMCD = "WGTHPCTL", PARAM = "Weight-for-height/length percentile" ) )library(dplyr, warn.conflicts = FALSE) library(lubridate, warn.conflicts = FALSE) library(rlang, warn.conflicts = FALSE) library(admiral, warn.conflicts = FALSE) library(pharmaversesdtm, warn.conflicts = FALSE) # derive weight for height/length only for those under 2 years old using WHO # weight for length reference file advs <- pharmaversesdtm::dm_peds %>% select(USUBJID, BRTHDTC, SEX) %>% right_join(., pharmaversesdtm::vs_peds, by = "USUBJID") %>% mutate( VSDT = ymd(VSDTC), BRTHDT = ymd(BRTHDTC) ) %>% derive_vars_duration( new_var = AAGECUR, new_var_unit = AAGECURU, start_date = BRTHDT, end_date = VSDT, out_unit = "days" ) heights <- pharmaversesdtm::vs_peds %>% filter(VSTESTCD == "HEIGHT") %>% select(USUBJID, VSSTRESN, VSSTRESU, VSDTC) %>% rename( HGTTMP = VSSTRESN, HGTTMPU = VSSTRESU ) advs <- advs %>% right_join(., heights, by = c("USUBJID", "VSDTC")) advs_under2 <- advs %>% filter(AAGECUR < 730.5) who_under2 <- bind_rows( (admiralpeds::who_wt_for_lgth_boys %>% mutate( SEX = "M", height_unit = "cm" ) ), (admiralpeds::who_wt_for_lgth_girls %>% mutate( SEX = "F", height_unit = "cm" ) ) ) %>% rename( HEIGHT_LENGTH = Length, HEIGHT_LENGTHU = height_unit ) derive_params_growth_height( advs_under2, sex = SEX, height = HGTTMP, height_unit = HGTTMPU, meta_criteria = who_under2, parameter = VSTESTCD == "WEIGHT", analysis_var = VSSTRESN, who_correction = TRUE, set_values_to_sds = exprs( PARAMCD = "WGTHSDS", PARAM = "Weight-for-height/length z-score" ), set_values_to_pctl = exprs( PARAMCD = "WGTHPCTL", PARAM = "Weight-for-height/length percentile" ) )
WHO BMI-for-age charts for boys from day 0 (birth) to day 1856
who_bmi_for_age_boyswho_bmi_for_age_boys
A data frame with 1857 rows and 4 variables:
DayAge in days
LBox-Cox transformation for normality
MMedian
SCoefficient of variation
https://www.who.int/toolkits/child-growth-standards/standards/body-mass-index-for-age-bmi-for-age
Metadata:
cdc_bmiage,
cdc_htage,
cdc_wtage,
derive_interp_records(),
who_bmi_for_age_girls,
who_hc_for_age_boys,
who_hc_for_age_girls,
who_lgth_ht_for_age_boys,
who_lgth_ht_for_age_girls,
who_wt_for_age_boys,
who_wt_for_age_girls,
who_wt_for_lgth_boys,
who_wt_for_lgth_girls
WHO BMI-for-age charts for girls from day 0 (birth) to day 1856
who_bmi_for_age_girlswho_bmi_for_age_girls
A data frame with 1857 rows and 4 variables:
DayAge in days
LBox-Cox transformation for normality
MMedian
SCoefficient of variation
https://www.who.int/toolkits/child-growth-standards/standards/body-mass-index-for-age-bmi-for-age
Metadata:
cdc_bmiage,
cdc_htage,
cdc_wtage,
derive_interp_records(),
who_bmi_for_age_boys,
who_hc_for_age_boys,
who_hc_for_age_girls,
who_lgth_ht_for_age_boys,
who_lgth_ht_for_age_girls,
who_wt_for_age_boys,
who_wt_for_age_girls,
who_wt_for_lgth_boys,
who_wt_for_lgth_girls
WHO Head circumference-for-age charts for boys from day 0 (birth) to day 1856
who_hc_for_age_boyswho_hc_for_age_boys
A data frame with 1857 rows and 4 variables:
DayAge in days
LBox-Cox transformation for normality
MMedian
SCoefficient of variation
https://www.who.int/toolkits/child-growth-standards/standards/head-circumference-for-age
Metadata:
cdc_bmiage,
cdc_htage,
cdc_wtage,
derive_interp_records(),
who_bmi_for_age_boys,
who_bmi_for_age_girls,
who_hc_for_age_girls,
who_lgth_ht_for_age_boys,
who_lgth_ht_for_age_girls,
who_wt_for_age_boys,
who_wt_for_age_girls,
who_wt_for_lgth_boys,
who_wt_for_lgth_girls
WHO Head circumference-for-age charts for girls from day 0 (birth) to day 1856
who_hc_for_age_girlswho_hc_for_age_girls
A data frame with 1857 rows and 4 variables:
DayAge in days
LBox-Cox transformation for normality
MMedian
SCoefficient of variation
https://www.who.int/toolkits/child-growth-standards/standards/head-circumference-for-age
Metadata:
cdc_bmiage,
cdc_htage,
cdc_wtage,
derive_interp_records(),
who_bmi_for_age_boys,
who_bmi_for_age_girls,
who_hc_for_age_boys,
who_lgth_ht_for_age_boys,
who_lgth_ht_for_age_girls,
who_wt_for_age_boys,
who_wt_for_age_girls,
who_wt_for_lgth_boys,
who_wt_for_lgth_girls
WHO Length/height-for-age charts for boys from day 0 (birth) to day 1856
who_lgth_ht_for_age_boyswho_lgth_ht_for_age_boys
A data frame with 1857 rows and 4 variables:
DayAge in days
LBox-Cox transformation for normality
MMedian
SCoefficient of variation
https://www.who.int/tools/child-growth-standards/standards/length-height-for-age
Metadata:
cdc_bmiage,
cdc_htage,
cdc_wtage,
derive_interp_records(),
who_bmi_for_age_boys,
who_bmi_for_age_girls,
who_hc_for_age_boys,
who_hc_for_age_girls,
who_lgth_ht_for_age_girls,
who_wt_for_age_boys,
who_wt_for_age_girls,
who_wt_for_lgth_boys,
who_wt_for_lgth_girls
WHO Length/height-for-age charts for girls from day 0 (birth) to day 1856
who_lgth_ht_for_age_girlswho_lgth_ht_for_age_girls
A data frame with 1857 rows and 4 variables:
DayAge in days
LBox-Cox transformation for normality
MMedian
SCoefficient of variation
https://www.who.int/tools/child-growth-standards/standards/length-height-for-age
Metadata:
cdc_bmiage,
cdc_htage,
cdc_wtage,
derive_interp_records(),
who_bmi_for_age_boys,
who_bmi_for_age_girls,
who_hc_for_age_boys,
who_hc_for_age_girls,
who_lgth_ht_for_age_boys,
who_wt_for_age_boys,
who_wt_for_age_girls,
who_wt_for_lgth_boys,
who_wt_for_lgth_girls
WHO Weight-for-age charts for boys from day 0 (birth) to day 1856
who_wt_for_age_boyswho_wt_for_age_boys
A data frame with 1857 rows and 4 variables:
DayAge in days
LBox-Cox transformation for normality
MMedian
SCoefficient of variation
https://www.who.int/tools/child-growth-standards/standards/weight-for-age
Metadata:
cdc_bmiage,
cdc_htage,
cdc_wtage,
derive_interp_records(),
who_bmi_for_age_boys,
who_bmi_for_age_girls,
who_hc_for_age_boys,
who_hc_for_age_girls,
who_lgth_ht_for_age_boys,
who_lgth_ht_for_age_girls,
who_wt_for_age_girls,
who_wt_for_lgth_boys,
who_wt_for_lgth_girls
WHO Weight-for-age charts for girls from day 0 (birth) to day 1856
who_wt_for_age_girlswho_wt_for_age_girls
A data frame with 1857 rows and 4 variables:
DayAge in days
LBox-Cox transformation for normality
MMedian
SCoefficient of variation
https://www.who.int/tools/child-growth-standards/standards/weight-for-age
Metadata:
cdc_bmiage,
cdc_htage,
cdc_wtage,
derive_interp_records(),
who_bmi_for_age_boys,
who_bmi_for_age_girls,
who_hc_for_age_boys,
who_hc_for_age_girls,
who_lgth_ht_for_age_boys,
who_lgth_ht_for_age_girls,
who_wt_for_age_boys,
who_wt_for_lgth_boys,
who_wt_for_lgth_girls
WHO Weight-for-length charts for boys from 45cm to 110cm
who_wt_for_lgth_boyswho_wt_for_lgth_boys
A data frame with 651 rows and 4 variables:
LengthLength in cm
LBox-Cox transformation for normality
MMedian
SCoefficient of variation
https://www.who.int/tools/child-growth-standards/standards/weight-for-length-height
Metadata:
cdc_bmiage,
cdc_htage,
cdc_wtage,
derive_interp_records(),
who_bmi_for_age_boys,
who_bmi_for_age_girls,
who_hc_for_age_boys,
who_hc_for_age_girls,
who_lgth_ht_for_age_boys,
who_lgth_ht_for_age_girls,
who_wt_for_age_boys,
who_wt_for_age_girls,
who_wt_for_lgth_girls
WHO Weight-for-length charts for girls from 45cm to 110cm
who_wt_for_lgth_girlswho_wt_for_lgth_girls
A data frame with 651 rows and 4 variables:
LengthLength in cm
LBox-Cox transformation for normality
MMedian
SCoefficient of variation
https://www.who.int/tools/child-growth-standards/standards/weight-for-length-height
Metadata:
cdc_bmiage,
cdc_htage,
cdc_wtage,
derive_interp_records(),
who_bmi_for_age_boys,
who_bmi_for_age_girls,
who_hc_for_age_boys,
who_hc_for_age_girls,
who_lgth_ht_for_age_boys,
who_lgth_ht_for_age_girls,
who_wt_for_age_boys,
who_wt_for_age_girls,
who_wt_for_lgth_boys