Changes in version 1.4.1 (2026-05-21) Documentation - A new vignette "Explore ADaM Templates" was added to the "Get Started" menu. It displays the {admiralonco} templates. (#341) Changes in version 1.4.0 (2026-01-29) New Features - The deprecated function date_source() was copied to {admiralonco} to provide a deprecation message rather than a deprecation warning. For this to have an effect the {admiralonco} package must be loaded after the {admiral} package. (#319) Breaking Changes - The following functions/arguments are entering the next phase of the deprecation process: Phase 1 (message) - derive_param_bor() is deprecated in favor of admiral::derive_extreme_event(). (#320) - derive_param_clinbenefit() is deprecated in favor of admiral::derive_extreme_event(). (#320) - derive_param_confirmed_bor() is deprecated in favor of admiral::derive_extreme_event(). (#320) - derive_param_confirmed_resp() is deprecated in favor of admiral::derive_extreme_event(). (#320) - derive_param_response() is deprecated in favor of admiral::derive_extreme_event(). (#320) - filter_pd() is deprecated in favor of admiral::filter_relative(). (#320) Phase 2 (warning) No functions or arguments in this phase Phase 3 (error) - The aval_fun argument in derive_param_bor(), derive_param_clinbenefit(), derive_param_confirmed_bor(), derive_param_confirmed_resp(), and derive_param_response() is deprecated in favor of the set_values_to argument. Phase 4 (removed) No functions or arguments in this phase Documentation - PSA response endpoints were added to the "Creating ADRS with Prostate Cancer Working Group 3 (PCWG3) Criteria" vignette. (#317) - The response values in the "Creating ADRS with Prostate Cancer Working Group 3 (PCWG3) Criteria" vignette were aligned to the standard terminology and the data issue in the RS domain was fixed. (#313) - The wording in the "Bone Response Categories Based on PCWG3 Guidelines" section of the "Creating ADRS with Prostate Cancer Working Group 3 (PCWG3) Criteria" vignette was improved. (#314) - The "Ask AI" widget was added to the bottom right of each page. It enables users to ask questions about {admiralonco} and receive answers from an LLM. It is trained on the documentation of the admiral packages and provided by kapa.ai. (#326) - A link to the {admiral} ecosystem page was added to the home page sidebar and main text. (#318) Changes in version 1.3.0 (2025-09-01) Documentation - New vignette "Creating ADRS with Prostate Cancer Working Group 3 (PCWG3) Criteria". (#304) - Display ANL01FL in the NADIR derivation in the ADTR vignette. (#305) Changes in version 1.2.0 (2025-01-27) Documentation - New vignette "Creating ADRS with GCIG Criteria". (#294) - The vignettes "Creating a Basic ADRS" and "Creating ADRS (Including Non-standard Endpoints)" were updated to describe how the case CR followed by PR is handled. (#276) - The documentation of the time-to-event source objects was fixed. (#293) Changes in version 1.1.0 (2024-06-19) Documentation - New vignette "Creating ADRS with IMWG Criteria". (#277) Updates of Existing Functions - Replaced hard coding of exprs(USUBJID, STUDYID) and exprs(USUBJID) with get_admiral_option("subject_keys") so the argument is flexible and can be changed from the default by the user. (#281) Changes in version 1.0.0 (2023-12-20) Updates of Existing Functions - The bor_ne event object was updated such that CR and PR are additionally considered as event. This ensures that the confirmed best overall response for a patient with a single CR or PR assessment is derived as "NE" instead of "MISSING". (#253) Documentation - New vignette "Creating ADRS with iRECIST endpoints". (#233) - All vignettes and templates were updated to be in line with the changes in {admiral} (see Breaking Changes for details)(#256). Breaking Changes - The derive_*() functions were superseded in favor of derive_extreme_event(). Any superseded functions can continue to be used as demonstrated via the "Basic ADRS" vignette, as they will remain supported and won't be deprecated in the near future. (#256) - The filter_pd() function was superseded in favor of filter_relative(). (#256) - The function call_aval_fun(), which was deprecated in admiralonco 0.4.0, has been removed. (#256) Various - Website now has button/links to Slack channel and GitHub Issues. (#262) Changes in version 0.5.0 (2023-09-14) New Features - Oncology specific events are provided for deriving oncology parameters with admiral::derive_extreme_event(). (#234) Documentation - The ADRS vignette and template were split into two (#234): - A basic version which uses the {admiralonco} functions to cover standard RECIST 1.1. - A more flexible version which uses admiral::derive_extreme_event(). This should be used if non-standard ADRS parameters should be implemented or non-standard response values should be considered. This version can also be used as a starting point for implementing other response criteria than RECIST 1.1, e.g., iRECIST or International Myeloma Working Group (IMWG) criteria for the diagnosis of multiple myeloma. - The ADRS vignette and template were updated such that test data from {pharmaversesdtm} instead of {admiral.test} is used. (#226) - The "Create ADTR" vignette and the ADTR template were updated such that test data from {pharmaversesdtm} instead of {admiral.test} is used. (#247) - The confirmed response derivation was fixed in the basic ADRS vignette and template. When calling derive_param_confirmed_resp() the filter_source argument has to be set to PARAMCD == "OVR" & ANL01FL == "Y" instead of PARAMCD == "OVR" & AVALC %in% c("CR", "PR") & ANL01FL == "Y". Otherwise, responses like CR, NE, NE, CR are considered as confirmed response. (#245) Changes in version 0.4.0 (2023-06-12) Documentation - New vignette "Creating and Using New Anti-Cancer Start Date" (#17) - "Create ADRS" and "Create ADTTE" vignette has been updated to include a link to "Creating and Using New Anti-Cancer Start Date" vignette New Features - Added a "Report a bug" link to {admiralonco} website (#211) - Added a section regarding dependencies to the {admiralonco} website (#223) - Vignettes and templates were updated due to changes in admiral and admiralonco: (#216) - The AVAL variable is now populated via the set_values_to argument as the aval_fun argument was deprecated. - admiral::derive_param_extreme_event() calls were replaced by admiral::derive_extreme_records() calls due to deprecation of admiral::derive_param_extreme_event(). - admiral::derive_param_exist_flag() calls were updated as the dataset_adsl argument was renamed to dataset_ref. Breaking Changes - Function derive_param_lasta(), which was deprecated in admiralonco 0.2.0, has been removed. (#216) - The aval_fun argument of derive_param_bor(), derive_param_clinbenefit(), derive_param_confirmed_bor(), derive_param_confirmed_resp(), derive_param_response() was deprecated in favor of the set_values_to argument. (#216) - The call_aval_fun() function was deprecated in favor or admiraldev::process_set_values_to(). (#216) Changes in version 0.3.0 (2023-03-14) Breaking Changes - All function arguments which expected a list of quosures created by vars() are now expecting a list of expressions created by exprs(). For example, instead of by_vars = vars(STUDYID, USUBJID) by_vars = exprs(STUDYID, USUBJID) must be used now. (#197) Documentation - New vignette "Create ADTR" (#16) Various - ADTTE template simplified for duration of response in line with admiral::derive_param_tte() enhancement (#203) Changes in version 0.2.0 (2022-12-07) Updates of Existing Functions - Functions that use subject_keys as a function argument now default to get_admiral_option("subject_keys")instead of vars(STUDYID, USUBJID) to allow users to change the variables that uniquely identify a subject once using set_admiral_options() to avoid several instances of find + replace in a script. (#175) Breaking Changes - Function derive_param_lasta() has been deprecated. Please use admiral::derive_param_extreme_event() instead (#89). Documentation - Showed alternative approach in ADRS vignette for filtering out assessments after progressive disease compared to source_pd argument (#168) - Extra terminology added for Independent Review Facility (IRF) as Blinded Independent Central Review (BICR) to make vignettes more accessible (#187) Various - Templates now save datasets as .rds instead of .rda (#177) Changes in version 0.1.0 (2022-09-13) - Initial package release focused mainly on solid tumor / RECIST v1.1.